The swine flu. Didn’t go so well. As his likely chief of staff said:
“It is purely a fortuity that this isn’t one of the great mass casualty events in American history,” Ron Klain, who was Biden’s chief of staff at the time, said of H1N1 in 2019. “It had nothing to do with us doing anything right. It just had to do with luck. If anyone thinks that this can’t happen again, they don’t have to go back to 1918, they just have to go back to 2009, 2010 and imagine a virus with a different lethality, and you can just do the math on that.”
https://www.politico.com/news/2020/05/04/joe-biden-contain-h1n1-virus-232992
Same guy said Trump wasn’t ready. Guess it took one to know one:
https://www.theatlantic.com/ideas/archive/2020/01/now-trump-needs-deep-state-fight-coronavirus/605752/